The provides support and information to gay men about recreational drugs and their health implications.
The campaign's website features a resident drugs counsellor to answer visitors' questions anonymously and explains how 12 different drugs, such as acid, alcohol and cannabis, affect health, sexual behaviour and HIV medication.
It also gives guidance on the legality of recreational drug use.
Dominic Edwardes, head of marketing at Terrence Higgins Trust, said: "'Drugfucked' makes great use of animation, music and interactive elements to deliver vital health information to a hard-to-reach target group, in a way that is both engaging and entertaining."
Global Beach created the site in Flash and HTML and used Ajax technology to allow real-time visual updates. The site also has integrated analytics to enable in-depth customer insight and measurability.
Prakash Patel, managing partner at Global Beach, said: "The 'Drugfucked' website demonstrates how creative can take a central role in helping to balance the emotional and serious aspects of a message, while providing an engaging and functional design."