The three, who had a popular radio show on alternative radio station Xfm that later became a hugely popular podcast on Guardian Unlimited, will present a two-hour special combining their irreverent humour with their all-time favourite tracks.
Sammy Jacob, founder of Xfm and managing director of NME Radio, said: "Hearing Ricky, Steve and Karl in action again will no doubt keep me on my toes.
"I used to bury myself hearing Ricky and Steve on air in 1997 fearing we would lose our license each time they went on.
"Having Karl on board has only made matters worse. I look forward to some compelling radio."
When 'The Ricky Gervais Show' ran as a podcast on Guardian Unlimited it was downloaded more than 2m times.
begins on June 2 and the two hour show will be aired each day from June 9 at varying times between 1pm and 9pm, and will be available to listen again on demand via NME.com.
NME Radio will be broadcast on Sky, Virgin Media, NME.com/radio and in various locations on DAB. The station will also be available on FM at various times around the UK via a series of RSL trial broadcasts commencing in London on October 6.
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