Users will be able to click on products from a range of fashion retailers featured in the magazine and on and buy them instantly through the Fabulous Shop.
The service, created by visual browser company Pixsta, fully integrates editorial content and shopping online and will offer discounted prices.
Lara Kelly, head of e-commerce at News International, said: "This is the first time a publisher has tackled the difficult task of fully integrating and cross referencing from magazine to e-commerce site.
"The final product is a fully interactive experience for readers and online users to enjoy, driving traffic and transactions."
Fabulous magazine and the online shop are launching this Sunday, February 3.