From 7am on Monday (14 January), members of the public will have the opportunity to register their interest via by filling out an online form.
Applicants will need to be 16 or older to apply, be eligible to work in the UK and available for at least eight days during the Games between 23 July and 3 August 2014. They will also need to be available to attend interviews, training and uniform collection in Glasgow in the lead-up to the Games.
Entries will remain open for just under seven weeks, with the closing date set for Thursday 28 February.
According to Glasgow 2014, no previous experience is necessary for the majority of roles with the emphasis being on finding people who are "friendly, welcoming and dedicated to making the Games a success". Those suited to more specialist roles will be able to list their skills on the form.
All applications will be reviewed at the end of the process with around 25,000 successful applicants then being invited for informal interviews at the purpose-built Volunteer Centre from April 2013.
The process will be the biggest peace-time deployment of volunteers for a common cause Scotland has ever seen and draws synergies with the army of 70,000 Games Makers recruited to stage the London 2012 Olympic and Paralympic Games.
David Grevemberg, Glasgow 2014 chief executive, described the opening of applications as a "landmark moment".
"The volunteers will be at the heart of an unforgettable Glasgow 2014 Commonwealth Games and the huge enthusiasm of those who have taken to social media to express their excitement and interest to volunteer has been overwhelming," he said.
"We have a wide range of general roles available as well as specialist positions and we have always emphasised that what matters most is a smiling face, a winning attitude and friendly banter – qualities I know Scotland and Glasgow will deliver in abundance."
Comment below and let us know what you think.
For more in-depth and print-only features, showcases and interviews with world-leading brands, don't miss the next issue of Event magazine by