will run for five months on Microsoft's MSN platform, spanning ten European countries, including the UK, Belgium, France, Germany, Italy, Netherlands, Spain and Sweden.
The site, which was developed by Microsoft Advertising's branded entertainment and experiences team (BEET), features a range of information relevant to small businesses, from raising finance for growth, to developing a mobile workforce and staying afloat in an economic downturn.
It also features tips from Meaden, the small business guru and one of the investors on the BBC's 'Dragon's Den'.
Users can ask Meaden questions, comment on articles or share advice and recommendations with each other.
They will also be able to instant message or email the content hosted on the site to colleagues, print out the articles or comments and add links to their blogs and profiles.
Rob Clark, director of consumer Inkjet business at Epson Europe, said: "Through this exceptional project, Epson and Microsoft are providing the tools for businesses to excel in productivity and efficiency, especially essential in the current economic climate.
"The site provides a resource for small business owners and entrepreneurs to learn from and share with peers and experts alike."
It is the first time that Microsoft and Epson have worked together on a branded campaign of this kind.
The site will be supported with ads across the broader Microsoft Advertising network, including Office Online.
There will also be a number of editorial placements across local MSN portals relating to the topics covered.
Tom Brunner, brand strategist for BEET International, Microsoft Advertising, said: "This multinational campaign will combine Microsoft's innovative technology and established online audience to help Epson reach an important and far-reaching audience of small business owners.
"We have created an interactive digital experience that keeps a unified brand voice, delivers Epson's campaign message and enables them to build a community for this business audience."