The magazine group, which publishes Vanity Fair and Vogue, has partnered with Acxiom for more than a decade around its direct mail marketing and, more recently, its digital campaigns to reach its 40m subscribers.
Greg Hogue, an Acxiom Media executive, said: "We're excited by the opportunity to build on our strong business relationship with Condé Nast.
"I am confident that our hosted database solution will continue to enhance Condé Nast's marketing return on investment and shape its integrated communications strategy."
Robert Schroko, vice-president of database marketing and analytics at Condé Nast, said: "Acxiom is a trusted business partner and an industry leader in helping companies like Condé Nast obtain a complete and accurate view of each subscriber and their value. We are pleased to continue the partnership."