The Prince is scheduled to make a plea to today's youth on MySpace followed by the online premiere of a 90-second public awareness film, which is also expected to be broadcast on major television networks.
Details of the film, which was produced by advertising agency Hurrell Moseley Dawson & Grimmer, have been kept secret, but the Prince is said to play a major role.
Hollywood actor Harrison Ford also appears in the film, as well as other members of the royal family.
According to the Daily Telegraph, Prince Charles is expected to say: "One of the internet's great strengths is that it can enable diverse communities to come together to ensure that everybody's views and actions can really be made to count.
"It provides the potential to create global determination for change on a vitally important issue."
The Prince's embrace of social networking is a volte face of the message he delivered last year, when he said technology dependence had left many people detached from nature.
His MySpace appearance follows in the footsteps of the Queen, who sent her first official email last week to mark the 60th anniversary of the Commonwealth.
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