The campaign, created by The Assembly, launches on 16 September and will run across sites on the London Underground and national train stations.
It will also include a digital and social media push and experiential activity themed around the Cold War, which is the subject of the book.
The activity is aimed at bringing in a younger audience, as well as appealing to the spy genre’s traditional readership.
The Assembly won the account in July after a competitive pitch against undisclosed agencies.
John le Carré moved to Penguin last autumn, after 38 years at Hodder & Stoughton.
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