St Luke's will direct communication for the initial launch of the and as part of that will create a viral campaign, which will run later this month.
My-Wardrobe.com currently sells women's designer goods, only previously offering men's accessories such as sunglasses and scarves.
Phil Teer, planning partner at St Luke's, said: "My-Wardrobe.com is an exciting brand with massive ambition and lots to say for itself.
"It's a pleasure to be working with them as we expand our digital and content capability."