Part of the plan being overseen by Guy Hands, the equity group's chief executive officer, is to drop thousands of artists from EMI's roster, which includes names such as the Rolling Stones, Norah Jones, Iron Maiden, Kylie Minogue and the Beastie Boys.
The cuts mean one in three staff at EMI will lose their jobs and many labels will be closed down.
Coldplay, headed by Chris Martin, has said the band might go on strike unless they are given assurances over marketing.
Likewise, Robbie Williams, who signed a record breaking five album £80m deal in 2002, has said he will also go on strike against the new owners and withhold his next album. However, this might be less of a blow considering the disappointing sales of his last poorly received album.
The new management, which bought the firm in a £3.2bn deal last year, is reported to be planning to employ focus groups as part of marketing. The move is likely to further worsen relations with some artists who will see it as an anathema to the creative process.
An EMI executive told the Sunday Telegraph: "When EMI releases a record it does no market research about whether people like the record or not."
The job cuts will be announced in a series of meetings at EMI's global offices beginning in London tomorrow. The meeting will be held at the Odeon Cinema in Kensington.
Robbie Williams's manager, Tim Clark, has called on members of the UK Managers Forum to turn up at the meeting.
"Robbie Williams has no intention of delivering a new album until he is convinced that the company can do a proper distribution and marketing job," Clark said.
Many administration jobs will also go as duplication of staff at individual labels disappears. All these jobs will be centralised and the company split into two divisions, comprising creative and back office.
Roger Ames, EMI's US chief, will oversee signings and artists in the US and UK, and Jean-François Cecillon will do the same internationally.
Hands will also tell staff that £200m will be injected into EMI, which makes over half of its profit from its back catalogue, including the Beatles and the Rolling Stones.
However, CD sales are falling rapidly and while digital sales are rising they are not doing so fast enough to make up for declining CD sales.