The programme kicks off on 21 June with a "burst of events" around the country highlighted by a series of concerts in Derry, Stirling, Birmingham and Cumbria.
Jude Law, Tracey Emin and Yoko Ono are just some of the names said to be involved in
In London, the Mayor's Office is planning events for all 33 boroughs aimed at creating "unforgettable experiences" for those attending.
Organisers say there will be more than 10 million chances to see free London 2012 Festival events throughout the UK.
BBC Radio 1 will stage its biggest-ever, free live music event in Hackney with six stages and more than 80 international and UK artists, bands and DJs, while Lake Windermere will host a free light and fire spectacular by pyrotechnic performers Les Commandos Percus.
"From 21 June to 9 September 2012, across the whole of the UK, new work from the best artists, musicians, writers, comedians, film makers and other creative talent will be presented in the largest festival in the country," said Cultural Olympiad director Ruth Mackenzie.
"From food to fashion, street dance to digital, and pop to opera, the festival will offer once in a lifetime chance to be inspired by the best in the world."
The festival runs until 9 September 2012.
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