Gambino, who will be based at Sonico's headquarters in Buenos Aires, Argentina, will be responsible for defining the strategy and developing partnerships, with emphasis on increasing multi-device engagement and revenue through content and applications.
She said: "I am excited to join the social media experts at to help build a stronger and more sustainable bridge for brands and other potential partners focusing on growth markets."
Gambino held the position of global vice president of music and content at Bebo where she played a key role in accelerating the growth of the company.
Prior to , Gambino was vice president of commercial, strategy and digital media for MTV Networks.
She also worked in business development at the BBC where she led the development and launch of the BBC's first mobile and broadband services, including its iPlayer.
Rodrigo Teijeiro, Sonico CEO and founder, said: "Angel's global experience in taking key business development responsibilities in traditional and social media companies enables Sonico to enhance its human capital quality to continue adding value to our users while boosting our business."
Sonico was founded in July 2007 and markets itself as "the social network of Latin America that organises people's lives". The site has over 42 million registered users.