This will involve the creation of a test portal in five European markets, including the UK, where UNICEF aims to create a 'best-in-class' e-greetings site.
Interactive marketing agency Fullsix won the business in a seven-way competitive pitch.
Roger Keczkes, UNICEF Geneva brand group head, said: "UNICEF is eager to meet consumer demand with a range of electronic greetings."
Steve Baer, chief operating officer at Fullsix, said: "We will be investigating whether people will pay for e-greetings and mobile greetings from the site."