People will be able to download one of four desktop pets to play with from a PDSA website. Users will be asked, but not required, to make a £1 donation using their credit card.
PDSA area fundraising manager Emma Cordery said the main purpose of the desktop pet is to raise awareness of its fund-raising events such as trekking along Peru's Inca trail.
Users can also opt to receive email news flashes about PDSA events, which will be delivered via their pet through a speech bubble.
DM agency LIDA created and implemented the PDSA campaign, which will be promoted using online and print advertising.
The first cyberpet was a goldfish called MOPy Fish which London-based news media company Global Beach created in 1997 for Hewlett-Packard to encourage office workers to do Multiple Original Printing on their printer rather than always using the photocopier.