The News Corp-owned social networking site will launch a mobile version of MySpace supported by advertising.
Initially it will operate in the US, but will be rolled out to the international versions of MySpace in the future.
The launch of a mobile service comes as the speed of the mobile internet continues to increase and becomes a major focus for mobile phone operators. MySpace, like other sites is available on a mobile phone, but the service is not optimised for mobile use and so can be difficult to use.
Like the PC version of MySpace, the service will allow users to send and receive messages, add friends, blog, post pictures or search.
The service is being launched by Fox Interactive Media, which oversees News Corp interactive strategy. The unit also has plans to launch mobile versions of FoxSports.com, sharing site Photobucket and entertainment site IGN.com as well as versions of local Fox stations.
John Smelzer, senior vice president of mobile at Fox Interactive, said: "Accessing the Internet from your mobile phone will soon be as common as text messaging and voice calling. Over time, the most targeted ads will be on mobile."
The free to access version of mobile MySpace follows a premium paid-for service that News Corp had been experimenting with.
Unlike the ad-supported service that launches today, mobile MySpace users used to pay around $3 a month to access a mobile site. The ads on the new mobile service are being provided by mobile ad company Millennial Media.
Paul Palmieri, chief executive of Millennial Media, said: "Mobile is the most personal device that a consumer owns. Next to your keys and wallet and maybe a pen that you walk around with. You're targeting consumers wherever they are."
The launch follows the news that MySpace is to use data-mining software to tailor advertising to its 110m users worldwide. The technology is supposed to improve the likelihood of members clicking on ads by an average 80%.