The show will take place on Sunday 7 November at multifunctional sports complex Caja Magica (Spanish for 'The Magic Box').
This is the second time Spain has hosted the event, which was held in Barcelona in 2002.
"Madrid is the ideal host city for this year's event because we are also celebrating the tenth anniversary of MTV Spain," said Antonio Campo Dall'Orto, executive vice-president of music brands and managing director of South Europe for MTVNI. "The spirit, culture and vitality of the city and its people, coupled with MTV's ability to deliver unique, star-studded experiences, promise to make this year's EMAs truly spectacular,"
Last year's event took place in Berlin and was hosted by singer Katy Perry.
Past performers have included global superstars Beyoncé, Foo Fighters, Jay-Z, Madonna, Prince, REM and U2.
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