The campaign, created by Origin Creative Design, goes live this week featuring the strapline 'It all adds up'.
It has been developed following market research that is being undertaken to track public confidence across Merseyside and to find out what really matters to people at a local level.
The aim is to communicate Merseyside Police's successes over the past twelve months.
The campaign will feature across outdoor and ambient media, building wraps, mobile exhibitions as well as on social media websites.
It will also run on the Merseyside Police magazine and digital channels to reach an internal audience.
Local and regional campaigns have been developed to ensure the right issues are communicated in the most appropriate way to each audience.
One local poster for residents of Hoylake and West Kirby reads: "567 bottles of alcohol taken from young people and adults in Hoylake and West Kirby in the last 4 months."
Mark Bottomley, managing director at Origin, said: "This is the largest co-ordinated campaign ever undertaken by Merseyside Police and will deliver the messages that really matter to the people that live there.
"The strategy addresses both an internal and external audience to communicate the Force's approachability and friendliness as well as its successes.
"To make an impact, the creative execution needed to be immediate, accessible, versatile and immersive.
"Our work expresses the cumulative actions and achievements of the police substantiated by numbers and facts."
The 18-month campaign will evolve to meet the changing needs of the Merseyside Police, and to address the most significant developing issues.
Bottomley said: "The challenge for us has been to develop a creative idea that will work at both regional and local levels.
"With this approach, we can deliver targeted messages directly relevant to local communities.
"The use of ambient media will be pivotal to the success of the campaign, as it allows a high degree of flexibility and the localisation of messages to tackle particular neighbourhood issues."
