The winning entry beat stiff competition from a shortlist that included Marketing Databasics, Tequila\London and Rocket Science.
Marriott was seeking to identify people with a high propensity to buy UK leisure breaks and used data insight to change the booking system.
Judges commended the data-driven aspects of the campaign and its impressive ROI figures.
The awards were presented at the Grosvenor House Hotel in London last month. More than 300 guests attended the evening, which was held in association with Royal Mail.