The covers feature a mix of models and designers from the fashion industry: Coco Rocha, Helena Christensen, John Galliano and Naomi Campbell as well as actress Kate Hudson.
Group publisher of Elle, Rita Lewis, said the 25th anniversary issue was a chance to "showcase all the work we have realised over the past two years since we repositioned Elle".
In January 2008 the magazine was re-launched to become more of a competitor for high-end fashion titles Vogue and Harper’s Bazaar rather than a mid-market populist title.
Lewis added: "We felt considering the range and depth of content which we have realised since the re-launch it was right and appropriate to say the 25th anniversary issue is the best Elle ever."
The £200,000 campaign spans press, outdoor and digital media and was created in-house with media planned and bought by MEC.
Elle will be supported by more advertising activity next year.