It has appointed direct shop Arc UK to handle the work following a three-way pitch against Harrison Troughton Wunderman and Joshua.
The agency will analyse data to help the charity better target its current donor base, as well as create a series of initiatives targeting new donors, which will launch in April.
The charity is hoping to raise awareness of the condition as it fights controversial recommendations announced by the National Institute for Health and Clinical Excellence (NICE) last week.
NICE has recommended that Alzheimer's drugs be made available only to people already in the moderate stages of the disease.
According to the Alzheimer's Society, about 750,000 people in the UK have dementia. About half suffer from Alzheimer's and 18,000 of these are under the age of 65.
The society spends the bulk of its marketing budget on direct mail, according to Nielsen Media Research; it spent more than £1.3m on direct mail in the 10 months to September, with the remainder of its budget going on press and DRTV.
The Alzheimer's Society's campaign against the NICE recommendations is being supported by celebrity brand ambassadors including Dame Judy Dench.
The charity is also campaigning for health authorities to research and record numbers and needs of people suffering from dementia in order to provide for them.