Weston joins from email marketing company Silverpop where he held the position of managing director for EMEA.
In his new role at Wunderloop he will be responsible for the development of new markets.
During his career Weston spent a stint as key account manager at Yahoo! UK & Ireland, before starting his own interactive marketing agency, Digital Oxygen.
After the sale of Digital Oxygen to Silverpop, Weston took over the European side of the business.
Weston said: "Going forward, integrated targeting technologies will be the crucial tool for optimally leveraging the competitive edge of digital media.
"Wunderloop is the market leader in this field, and my goal is to further enhance this position internationally."
Torsten Ahlers, Wunderloop CEO, said: "We are already a leading provider of integrated targeting solutions in many countries. Now we want to enter the American market.
"The experience we're gaining in Europe is very important for a successful US launch. In Mike Weston, we have the right man on board to continue our global expansion."