At TMG, Gill developed a number of award-winning sites, including the Home Office and ReedSmith.
He is widely regarded as a pioneer of design techniques for large-scale, complex projects.
During his career, Gill has led design teams on clients including Apple, Unilever and Cisco.
Prior to TMG, Gill held positions at Perception/DM, SmartAxis BV and BBDP.
Lyndon Hale, Wheel's executive creative director, said: "Wheel is committed to recruiting people with the best credentials so I am delighted to welcome someone of Simon's calibre to the team. His award-winning experience makes him an ideal fit for Wheel."
Gill said: "Wheel leads the digital industry in the UK and, as such, represents a fresh and exciting challenge for me.
"I am looking forward to working in a full-service environment with the cream of digital creative talent."
If you have an opinion on this or any other issue raised on Brand Republic, join the debate in the .