The poster and digital ad campaign will run nationwide from today, aiming to build on the success of last year's 'Pass on Something Good' campaign.
One ad features a chalice glass in the centre of an arctic surrounding, featuring penguins, icebergs and wooden kegs dated 1366 that symbolize the brand's chilled positioning and brewing heritage.
A strapline at the bottom of the ad reads: "A chalice crafted to keep your beer colder for longer."
The campaign will run on 3278 sites nationally. There will be a large focus on the London Underground to reach the key audience of ABC1 males.
InBev claims the campaign is the single biggest monthly spend by any lager or cider brand in almost 18 months.
Stuart MacFarlane, president of InBev UK & Ireland, said: "This high-impact advertising burst will communicate the key brand credentials in a strong visual fashion that a significant number of lager drinkers will readily buy into.
"It underlines the craftsmanship associated with the brand and the fact that the innovative chalice glass is crafted to keep the beer colder for longer -- to enhance the drinking experience for people who really appreciate top-quality lager.
"The campaign is focused on a very short time period to ensure it makes an immediate impact with the brand's target audience at the start of the summer which is a key period for premium lager business."
InBev said it has further activity planned for the remainder of 2008, which will continue to market Stella Artois as the best quality lager brand.