The , created by Dan Norris and Ray Shaughnessy at Wieden & Kennedy, aim to challenge the traditional charity model of hitting people with "guilt" statistics, by explaining that saving children's lives is actually very simple.
Each execution in the campaign details one of seven life-saving solutions, each costing between £1 and £5.
The charity reveals that to help a child make it to their fifth birthday could be as easy as providing a £5 mosquito net or £1 rehydration salts to help a child recover from diarrhoea.
The first 30-second TV spot, "", has been directed and animated by Simon Robson, and is voiced by Thomas Turgoose, the child star from the award-winning film 'This is England'.
It focuses on micro-nutrient peanut butter, which can be digested by shrunken stomachs and therefore keep malnourished children alive.
The ad ends with the strapline, "We save the children. Will you?", and the address.
Branding specialists Johnson Banks has also worked with Save the Children to develop a clearer brand positioning for the charity in the UK.
Children from around the world were asked to redraw the Save the Children logo and typeface. As a result the charity has incorporated 14 fonts designed by 10 children aged five to 12.
Over the next few months Save the Children will introduce lots of simple ways of saving a life, to help families interact with the charity's work around the world.
Joe Barrell, head of communications at Save the Children, said: "This is just the start of a three-year campaign to save children's lives. We will be using technology allowing families to get involved and show the world just how simple it is to save a child's life."
Kim Papworth, executive creative director at Wieden & Kennedy London, said: "The campaign style is very simple and graphic, which reflects how simple the solutions are that Save the Children has devised to save kids' lives."