The direct marketing review follows a creative agency review last year which culminated in the appointment of Catalyst last October. Feather Brooksbank handles the media account.
The appointed agency will work across all direct marketing activity for the charity. Its most recent campaigning issues have been on child poverty and the effect of HIV/AIDS and conflict in Africa.
The charity's account was held by Brann before its merger with ehs:realtime but the merged agency continued to work for the charity.
Earlier this year EHS Brann created a national press campaign which focused on the link between poverty and child prostitution using the line: "Rachael is so poor she has to sell herself."
The charity has also run ads and direct marketing to raise awareness and funds during conflict in Afghanistan. Other than direct mail, the bulk of Save the Children's spend is focused on press advertising, but it has also run DRTV on Channel 4 and Channel 5.
The charity consolidated its global direct marketing operations into London last year. The aim was for London to co-ordinate and set budgets for its below-the-line activity across 30 territories. In June it appointed the former Young & Rubicam director, Susan Scrimgeour, as its marketing director.
Save the Children confirmed it is reviewing the account. However, Nick Marsh, its direct marketing manager, refused to comment. It is also working on a revamp of its retail brand image.