The vehicle Shana was travelling in was stopped and, as he was getting out, an explosion killed him and two bystanders. His soundman, also in the vehicle, escaped serious injury.
Shana, 23, who had worked for Reuters in Gaza for more than three years, was wounded in August 2006 when an Israeli aircraft fired a missile at the vehicle he was travelling in.
He was described by Alastair Macdonald, bureau chief for Israel and the Palestinian territories, as "a gentle soul, happy and extremely bright, and one of the most skilled cameramen in Gaza who will be missed greatly by all his colleagues".
David Schlesinger, Reuters editor-in-chief, called for an investigation into the incident and said Reuters thoughts were with the family.
He said: "This tragic incident shows the risks journalists take every day to report the news. All governments and organisations have a responsibility to take the utmost care to protect professionals trying to do their jobs.
"Our thoughts are with his family. We request an immediate investigation into the incident by the Israeli Defence Forces."
Reuters has 70 journalists covering the Israeli and Palestinian region, 15 of which are in Gaza. Shana was part of the Gaza television team that won the News Event award at the annual Royal Television Society Television Awards in March 2008.
His death marks the first time Reuters has lost a journalist in Gaza.