
The jeans manufacturer will build on last year's sponsorship of the live music event as an official pan-European sponsor.
It will feature on all promotional material in the build-up to the show, including a presence on the on-air campaign for the event, all marketing and press materials, online on the MTV EMA microsite, and "on-the-ground consumer promotional activities in Frankfurt," according to Be Viacom, the brand solutions group within MTV’s parent company Viacom.
Dave Sibley, executive vice-president of Be Viacom, said: "Having Replay return for a second consecutive year speaks to the MTV EMA's unrivalled connection with the global youth audience, its credibility and sheer brand power."
Renaissance Hotels will be a digital sponsor for the UK, Germany and France, with activity in selected hotels.
Sibley added: "The 2012 MTV EMA offers Replay and Renaissance Hotels the ultimate vehicle to engage with young people in a targeted and powerful way.
Bob Bakish, president and chief executive of Viacom International Media Networks, said: "We're thrilled to be returning to Frankfurt and once again presenting the MTV EMA in such a vibrant and dynamic city. This year's show will definitely continue the EMA tradition of capturing the world’s attention through unforgettable performances and jaw-dropping moments."
Additional sponsors for the MTV EMAs will be announced in the coming weeks. The last time the awards were held in Frankfurt was 2001.
In , the creative media solutions arm of broadcaster Viacom, rebranded under the international banner Be Viacom, to reflect a move to brand engagement across the network.
Last year's awards took place in Belfast, with sponsors including Replay Jeans, Dell, Hyundai and Swatch.
Follow Mark Banham on Twitter