A total of 25,000 copies of Metro will be available in Liverpool from today, and in Cardiff from March 14 at selected bus and railway stations.
The new editions will increase Metro's national circulation to 1.1m, consolidating its position as the fourth-largest national weekday paper in the UK.
Introduced in March 1999 as a free newspaper for commuters, Metro is now available in 15 UK cities, including London, Manchester and Newcastle.
Steve Auckland, managing director of Metro, said: "We are delighted to be launching these new editions in partnership with Trinity Mirror and to be increasing our London circulation.
With the enormous amount of development taking place in Liverpool and Cardiff, we believe there is a large urbanite audience, which will relish Metro's unique format, concise news and local guide to what's on in the city."
The launches in Cardiff and Liverpool are being done as a partnership between Metro publisher Associated Newspapers and Trinity Mirror, which publishes the Liverpool Echo and the South Wales Echo in Cardiff.
Georgina Harvey, Trinity Mirror's managing director for regional newspapers, said: "This exciting addition to our portfolio allows us to tap into an affluent, young, 'urbanite' demographic, enhancing our offering to advertisers."
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