The "Glamcam", which has been a massive hit with users, will now feature more prominently on the home page. Before, it was just a button on the tool bar.
The video move will give a more prominent position to the 15- second and 30-second pre-roll video advertising.
The relaunched website will also have a new feature called The Body Plan, which will invite users to join up to a motivational programme to get fit for the summer, with exercises and tips e-mailed to subscribers from fitness expert Matt Roberts.
Different discussion rooms where users can chat about fashion, beauty, celebrity, love and relationships, and health and fitness will also be launched.
More features will be included on the site, such as articles by stylist Bay Garnett on vintage shopping. The site has dropped its Fashion Finder section, a search function for finding clothes, as Condé Nast has just launched its first stand-alone website Stylefinder.com, based on Fashion Finder. Stylefinder.com is the new site that will target 15 to 45-year-old women, providing information on a range of fashion and beauty items including high street and designer labels.
However, Condé Nast Interactive editor-in-chief Abigail Chisman said Glamour.com users will be directed to Stylefinder.com, and Glamour.com will have increased coverage of celebrity style.
Chisman added that the site would be more interactive.
"We are very much driving people from the articles into interactive areas," she said.
The world of websites targeting women is growing ever more competitive.
Last year, Condé Nast rival NatMags acquired women's online publishing group Handbag, and has twinned its magazines She and Company, with allaboutyou.com and getlippy.com respectively.