The redesign, the biggest in the title's 13-year history, will appear in shops from today with a coverprice of £3.99.
It has attracted a number of first-time Total Film advertisers including Intel, Nintendo, Bacardi and Oakley.
The layout introduces new regular sections such as a "dialogue" spread to showcase readers' comments from Twitter and the Total Film website.
The magazine, whose target reader is the 18-34 predominantly male cinema enthusiast, will also offer more reviews and in-depth features in each issue.
Aubrey Day, editor-in-chief of Total Film, said: "We haven't revamped the mag in three years and in that time a lot has changed.
"Movies are driven more by franchises now than they are by movie stars, Blu-Ray and downloads have come about and social media means all our readers talk to us on Facebook and Twitter."
Future hopes to broaden the brand’s reach by utilising multi-platforms as well as offering forthcoming mobile and event spin-offs.
Day added: "It's a fundamental revamp we haven’t just made the pages prettier, we've really stepped back and said this brand is being very successful, but how can we be bigger and better?."
Despite the strain on publishers in the past two years the publication's circulation has held relatively steady.
Total Film's average circulation in the July – December 2009 ABC period was 81,029 copies, down 6% year on year.
But during the same period, circulation at Bauer's Total Film rival Empire, was up 2.4% year on year to 194,239.
Day said: "Where we differ from Empire is that our priority is the movie goer, not the movie industry and I think that's more apparent with our redesign.
"We started the re-design from a good place, we're one of the few mags who were not hit as hard as some other areas in the industry. It's nice not to have to do a relaunch from a position of panic."
The number of visitors to TotalFilm.com in June was 379,934 according to Future-specific site stat audit software.
Nial Ferguson, publishing director of Future’s entertainment and tech lifestyle portfolio, said: "The website has been very successful and has grown considerably."
The Total Film iPhone app will launch in August and cost £1.79. It will be offer news, reviews and trailers from TotalFilm.com.
It will include cinema listings, show times and directions, as well as the ability to share content with friends through Facebook, Twitter and e-mail.
Separately, Total Film made the headlines this week when it mistakenly tweeted that Monday 5 July was the day that Marty McFly and Doc Brown time-travel to in the iconic eighties film 'Back To The Future II'.
The online buzz trended on Twitter and appeared in newspapers and other media around the world, before it was revealed as incorrect.
The magazine later mocked up an image of the time-travelling device seen in the film to display 5 July 2010.
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