Prior to her promotion, Johnson was working as head of the international division at the Omnicom-owned agency.
Her new role will involve working alongside her current clients such as Nissan and Vodafone, while continuing to increase the agency’s European work.
Mark Bullingham, managing director of Fuse EMEA, said: "Louise has done an incredible job running our Fuse International team, driving the growth of Fuse in the UK.
"She has helped create an industry-leading business that maximises all of the assets from the media group to deliver a strong proposition to clients.
"She is perfectly placed to both support our growth in Europe and drive our portfolio of international clients."
Johnson added: "The last three years have been fantastic, and my goal is to harness that dynamism to further grow the business."
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