The magazine will get a fresh logo, which has been updated to modernise the brand but also to echo the original logo of the magazine when it launched in 1964.
The re-introduction of a female cover model is designed to give the title a more glamorous edge, as well as indicating that women are as likely to be shopping for clothes as well as food.
Design changes, which have been gradually introduced over the past year, have seen the arrival of modern layouts, innovative use of typography and pictures.
The new-look edition will also come with a free 'Love it! Lose it!' diet booklet giving readers tips on how to lose a stone in a month and a special feature on the life of a Family Circle reader in 2004 compared with 40 years ago.
Julie Barton-Breck, editor of Family Circle, said: "In response to in-depth reader research, we've been reinforcing our appeal to busy, modern women and focusing on simple solutions to make their life easier.
"I believe that the reintroduction of a cover model, along with the other drop-in pictures and stand-out cover lines, reflects that approach."
Linda Swidenbank, publishing director, added: "Family Circle was the original supermarket magazine, and even today we sell more copies through supermarkets than anywhere else. But think how much they and UK society has changed in that time -- and Family Circle has evolved to reflect this."
In the latest set of ABCs, the magazine's circulation fell down 12.3% year-on-year to 130,940.
IPC Southbank announced in August that Family Circle editor Barton-Breck would be swapping roles with Essentials editor Karen Livermore from October.
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