The 6,000sqm Aspers casino will be the largest in the UK and will include a Sky Bar with views over the Olympic stadium.
Excel director of conferences and events James Rees said: "The opening of Aspers at Westfield is really good for us, as it provides our business visitors with another reason to stay close to our campus, which is at the very heart of London’s event district, and enjoy everything the East of London has to offer."
London & Partners director of business tourism and major events Tracy Halliwell said: "Aspers Westfield Stratford City is a major addition to London’s business tourism proposition, and its opening will further strengthen London’s reputation as the best city for business."
The casino will be open 24 hours a day, 364 days a year.
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