The drive, created by Watson Phillips Norman, shows images of children and adults living with poor-quality drinking water and sanitation. A voiceover, provided by Auf Wiedersehen Pet and Inspector Morse actor Kevin Whately, asks viewers to give £2 a month.
Mike Wade, head of central fundraising at WaterAid, said: 'We hope our latest campaign will alert more people to the fact that safe water and sanitation are basic human rights, which everyone in the world should have access to.'
The charity works in 17 countries to provide access to safe water and sanitation, as well as education about living hygienically.
The ad will run across digital terrestrial and satellite channels.