Second Life users will be invited to take part in a live question-and-answer session with the film's director, Michael Bay, producer Lorenzo di Bonaventura and selected cast members.
They will also be able to explore the high-security 'Sector 7' underground facility featured in the movie, access exclusive video content and download accessories to personalise their Second Live avatar.
The activity is being handled by film marketing agency Picture Production Company, which acquired a Second Life island last year to devote to integrated digital campaigns for clients.