The showcase, which will launch on September 27, is dubbed "the book" by the industry and is the only permanent record of the best creative work each year.
D&AD Global Awards jury members made the selection from more than 24,500 pieces of work entered from 61 countries.
Michael Hockney, D&AD chief executive, said: "The 2006 Annual is a source of inspiration to creative practitioners everywhere.
"The book contains analysis of the best work in the world by leading creative practitioners and further coverage of D&AD's range of activities. The design incorporates key elements of our recent rebrand."
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