The company, part of Cello Group, has enjoyed a period of "unprecedented business growth" and will now serve North America out of San Francisco.
The team will be headed up by Remi Abbas, vice-president of qualitative research and James Redden, vice-president of quantitative research, who drive new business in the area.
Called 2CV North America, the division will replicate the full range of services already offered in the UK including ethnographies, cultural analyses, segmentations and advanced analytic techniques.
This is the first stage of 2CV's expansion, with plans in the pipeline to establish further offices in North America as well as some in Asia and more in Europe.
Founder and chief executive Vincent Nolan said establishing the first of its international hubs in San Francisco was a "natural choice".
Nolan said: "[It's] home to some of our largest clients and, more broadly, of technological innovation.
"The move is part of 2CV’s broader business strategy to add scale and specialist services traditionally only available through the big corporate research houses."