In his new role, Weiss will be responsible for overseeing 180's creative output, working across brands including Adidas, Sony Consumer Electronics USA and MTV.
He will work closely with the agency's other creative director, William Gelner.
During his career, Weiss has worked on brands including Fox Sports, Guinness, Nike and ESPN.
He was also responsible for creating the iconic "There can only be one" campaign for the National Basketball Association.