The campaign, to find the perfect night out, will run during Ben Jones' Most Wanted show and starts next Monday (24 July).
Pre-promotions start this week, with Most Wanted listeners being asked to vote online for their perfect night out in the UK, at www.virginradio.co.uk. This information will then form the basis of questions for next week's Most Wanted evening shows.
One listener per night will win an all-paid trip to Amsterdam, the home of Amstel, while one online voter will win a night out in the British city voted most popular.
According to Amstel brand manager Toby Shaw, Virgin was selected on account of its ability to deliver millions of national 25 to 44-year-old listeners.
"We're partnering with Virgin Radio as they've delivered a great on-air and online mechanic that will connect with a key national audience," he said.
Amstel is currently aiming to promote a more continental style of drinking and encourages people to think differently, try something new and have a good time without going over the top.
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