The deal gives Simple access to channels including 4Music, Kiss, Smash Hits and The Box, with a series of ads and sponsorship idents.
The campaign kicks off today and with a three-week run of 20-second ads designed to reach secondary school kids before their end-of-term 'proms'.
The ads feature a call-to-action competition, in which children can enter on behalf of their school for a chance to have pop singer Daisy Dares You to sing at their end-of-term party, while runners-up can win iPods.
The second wave of the campaign will kick off in August, when 90-second ads will televise Daisy Dares You's school performance.
All the activity will be supported with 10-second sponsorship idents on each of Bauer's music TV channels.
Alex Pike, Simple's group marketing director, said: "Proms are completely on-trend with teens, and music is the ultimate vehicle to target them with our new Spotless Skin range.
"More than 1.4m 11 to 17 year-olds are currently buying medicated skincare to combat breakouts such as spots and blackheads, something they definitely want to avoid for their prom night."
The partnership was brokered by PHD/Drum, Simple and Bauer Media's TV sales and promotions team.
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