The swingeing cut represents about 14% of D'Arcy's New York staff, according to reports.
The loss of the account followed P&G's decision to consolidate its $75m (拢52.3m) global Pampers advertising account into Saatchi & Saatchi in New York. The US portion of the account was worth $30m.
It is understood that the redundancies are affecting all areas of the agency. The cuts follow the recent hiring of more than 10 staffers from Lowe & Partners to work on 拢35m Heineken account, which the agency won in February.
D'Arcy is part of the B|Com3 Group, which is being acquired by Saatchi's owner Publicis in a $3bn deal.
There has been speculation, which has not be ruled out by Publicis chairman and CEO Maurice Levy, that D'Arcy could find itself merged with sister B|Com3 agency Leo Burnett after the Publicis acquisition is complete.
If you have an opinion on this or any other issue raised on Brand Republic, join the debate in the