The title, which has recently run a series of press ads that highlight its strength in cities across the UK, is distributing direct mail to creative and media agencies in order to position itself as the "creative newspaper".
A large-format mailing will be sent this Friday to 500 senior agency people to emphasise that Metro is a "blank canvas" for creative ideas.
The mailing was created by Metro and its creative agency, Barrett Cernis.
It features a series of case studies and "60- Second Interviews" with clients from Capital Radio, Levi's and Adidas.
Karen Wall, the marketing director at Metro, said: "We've targeted creative agencies because we want to get them thinking about Metro early in the process."
Metro's ad revenue is growing on the back of circulation expansion that has taken it beyond the one million mark.
Launches in the East Midlands and Bristol last year helped to boost circulation.
Metro claims to have a younger, more affluent audience than many newspapers.
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