The brief for the business will be focused around pursuing the company's strategies of promoting the relevance and attainability of Harley-Davidson motorcycles in the EMEA region.
McCann Erickson Birmingham will act as lead agency working with Harley-Davidson's UK-based European marketing team and network of existing country agencies.
John Lewis, Harley-Davidson's European marketing director, said: "We've been really impressed, not only with McCann's creativity and holistic approach to media channels but also with the people involved.
"It's exciting to work with a great team from an excellent agency partner to help us as we seek to continue our strong growth in the EMEA markets. We are intent on fulfilling the dreams of a great many more Harley-Davidson customers in the future and McCann Erickson is the right partner to help us achieve our goals."
Jamie Heath, McCann Erickson Birmingham group account director, said: "We're very proud to be working for Harley-Davidson Europe. Harley-Davidson is without doubt a genuinely iconic brand globally. We're all very much looking forward to working with John and his European team as well as with their in-market colleagues and network of agencies across the region."
The company sells its motorbikes through 30 dealerships across the UK and Ireland.