The doughnut and coffee brand tasked Addiction London with creating the campaign, electing to use outdoor media, from posters to Oyster card holders.
The creative plays on the idea of doughnuts being an office treat and urges people to "think inside the box".
Three different executions bear the headlines "Impress the boss", "Brainstorming again?" and "Accidentally replied to all?".
Media space has been booked directly by Addiction London with CBS Outdoor. Ads will be located on the Underground and on mainline station concourses in an estimated £500,000 investment.
Since launching in the UK in 2003, the company has relied on point of sale, digital and PR activity.
Katie de Souza, head of marketing at Krispy Kreme UK, said: "We are excited to be testing advertising in the London area and see this as a great opportunity to connect with our target audience, communicating Krispy Kreme as a unique office treat."