Sachs' wife Melody said she was amazed that Ross should get nominated "with a mouth like his", acknowledging his talent but describing what he did as "so disgusting".
Her condemnation of Ross follows last year's 'Sachsgate' affair surrounding a series of lewd phone calls to the 'Fawlty Towers' actor in a BBC Radio 2 telephone prank. It drew more than 30,000 complaints from the public.
Sachs himself responded to news of the Bafta nomination with good grace.
Quoted in The Telegraph, he said: "One would question the reasons when it comes so quickly after what happened.
"I wonder how much it has to do with trying to comfort him? I don't know. That is how it happens. That is showbusiness."
Sachs went on to explain that he felt no animosity towards the BBC presenters, even saying: "Good luck to him."
John Beyer, the director of television watchdog Mediawatch, said: "I think it's a mistake for Jonathan Ross to get a nomination, but I'm not at all surprised.
"Bafta has a reputation for rewarding controversial people for the sake of it. They are completely out of step with public opinion."
In October last year, Ross and comedian Russell Brand left a series of indecent messages on Sachs' home answering machine. In one of them, Ross told Sachs that Brand "fucked" his granddaughter.
The debacle caused a public and media outcry and led to a three-month unpaid suspension for Ross and the resignations of Brand and Radio 2 controller Lesley Douglas.
Bafta committee member Andrew Newman, defended the decision to nominate Ross. He said: "This is a nomination for his performance on 'Friday Night with Jonathan Ross', so what he did on somebody else's radio show would not be a right thing to consider.
"It's not surprising that he's been nominated because he's one of the stalwarts of entertainment presenting."
Alongside Ross, other nominees in the entertainment performance category include Harry Hill for 'Harry Hill's TV Burp' and Stephen Fry for 'QI'.
Other programmes up for Bafta's include 'Hancock and Joan', 'The Curse of Steptoe' and 'Criminal Justice'; while 'Eastenders' actress June Brown, who plays Dot Cotton, was nominated for best actress for an episode-long monologue.
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