Hughston, who leaves without a job to go to, will not be replaced. His role will be covered by Michael Rebelo, the incoming managing director and Peter Lovatt, the vice chairman of Saatchi & Saatchi.
Hughston was previously managing director of Saatchi & Saatchi Interactive. He was appointed new business director in January, following the departure of Adam Kirby.
Robert Senior, the UK chief executive of the SSF Group, said: "Neil Hughston, new business director at Saatchi & Saatchi London, has decided to move on to a new challenge and we wish him well Michael Rebelo, incoming managing director and Peter Lovatt, the agency's vice chairman, will take joint responsibility for leading new business."
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