Thorogood left ITV in January after almost two years, which followed a four-year spell as head of lifestyle channels at UKTV. He has been working for a South East Asian broadcaster and joins Five in September.
Dan Chambers, Five's director of programmes, said: "Nick has a great track record in both terrestrial and digital broadcasting, which gives him the perfect background and experience to launch Five Life and Five US."
Initially available on Freeview, followed by satellite and cable, Five Life and Five US are the first extensions to the main channel, which will celebrate its 10th birthday next March.
Five US will extend the US programming familiar to Five viewers from shows such as 'CSI'. It has acquired dramas 'Shark', 'Vanished' and 'The Nine'.
Comedian Russell Kane has been signed to be the face of Five US, with a presenting role seeing him go behind the scenes of the channel's top shows and interview members of the US public for short films intended to punctuate the schedule.
Five Life is skewed towards a female audience and will offer drama, films, soaps and the pre-school strand Milkshake!.
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