The poster has been erected in Coventry, which is the home to Leanne Salt -- a 30-stone woman the tabloids have dubbed "Britain's fattest mother" who admitted to feeding her triplets chicken nuggets and burgers since they were six months old.
The poster features an image of a fat-cheeked, child about to take a bite out of a burger.
"Fight the fat," the poster reads. "Go veg."
Peta, not an organisation known for pulling its punches, explained that the same billboard was erected in County Durham in 2006.
It unsurprisingly drew complaints from people who Peta reckoned "have a vested interest in meat". The Advertising Standards Authority dismissed the complaints.
Poorva Joshipura, director of Peta, said: "The damage caused by meat-based diet is like a ticking time-bomb in kids.
"Vegetarian kids are slimmer, have more energy, get better grades and are all-round better off than their meat-eating peers. These are facts that Ms Salt and other parents should take to heart."
The poster is located in Coventry's New Union Street.
Earlier this month Peta wrote to Samsung, claiming that its "baa-studs" online ad features footage of cruelty to animals.