The paper claims that the new look, which hits newsstands on Monday, is the paper's most significant investment in the last 20 years.
The most dramatic change to its format is the launch of a standalone business section, which is being edited by former Sunday Times business editor William Lewis. The section will include a twice-weekly column written by former BBC business editor Jeff Randall.
The Daily Telegraph's editor Martin Newland explained that he wants to stay true to his readership's core market, while removing "obstacles to new readers".
"I want business to read like the sports section, to report deals like you would report a Liverpool versus Chelsea match," he said.
"It's a business section with a bit of GQ. Our sport has always been acknowledged as the most brilliant and comprehensive available anywhere. This new section will make it even more popular."
The new 24-page sports section will be feature articles written by well-known sporting commentators, including Alan Hansen, Michael Parkinson and Sebastian Coe.
The expanded features section in the main paper will relocate to the back pages and will continue to focus on news and reviews spanning art, film, fashion, health and lifestyle.
In last month's ABCs, The Daily Telegraph experienced a 0.84% drop in circulation to 904,660.
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