Corston, who will start his new role in August, has more than 20 years' experience in digital media, most recently at Agency.com, which he joined in 2005, and headed up digital operations at direct marketing agency Craik Jones Watson Mitchell Voelkel before that.
Corston said: "As the relationships between consumers and brands change so will that between clients and agencies, as we knew them.
"The role of innovation will play an increasingly critical part in business strategy and increasingly inform marketing communications. Sense Worldwide is uniquely placed to capitalise on this with the experience and intelligence of its global network and online services."
Prior to his time at Craik Jones, Corston ran his own company Arawak Interactive Marketing, which included Microsoft, Sony PlayStation and the British Heart Foundation among its clients.
Separately, Sense has appionted Barry Lustig as strategic director. Lustig joins from US interactive firm The Barbarian Group.
He also spent time at the World Economic Forum as manager for societal risk and at Dentsu, Tokyo as a creative strategist.
Jeremy Brown, chief executive of Sense Worldwide, said: "This is an extraordinary time in our eight year history.
"Digital media is both a communications channel and an aspect of product and service delivery itself and Nick's experience will be invaluable in mapping this to the business strategy of our clients. Barry's strategy experience on a global stage will give us an invaluable insight into helping client's bridge innovation and marketing strategy.
The appointments follow that of Steve Heron, who joined Sense as studio head last year from design consultancy Ideo.